High Activity PDRN Essence Barrier Strengthening For Sensitive Skin Care

• Technical Principle: Polydeoxyribonucleotide (PDRN) is a high-bioactivity polynucleotide polymer with a segmented DNA molecular structure. It activates skin adenosine A2A receptors and regulates multiple skin repair signaling pathways including FAK and AKT after percutaneous absorption. Different from traditional moisturizing ingredients, PDRN adopts a bionic skin repair mechanism, which accelerates the proliferation of dermal fibroblasts and keratinocytes, promotes microcirculation angiogenesis, and effectively inhibits inflammatory factors. It repairs damaged skin barriers from the cellular level, awakens skin self-regeneration ability, and realizes continuous soothing, anti-inflammation and tissue remodeling effects.
• Production Process: Medical-grade PDRN adopts standardized biological extraction and controlled fragmentation purification technology. High-purity natural nucleotide raw materials are selected and subjected to strict enzymatic digestion and deproteinization procedures to completely remove heterologous proteins, lipids and allergens. Through precise temperature-controlled cracking and graded molecular fragmentation, uniform and active short-chain PDRN fragments are screened. Multiple rounds of ultrafiltration, impurity removal and depuration are conducted to eliminate biological residues. The whole process is finished in a sterile low-temperature workshop, retaining high biological activity while ensuring zero sensitization, high stability and clinical safety.

Core Technical Parameters